A 25-year-old woman from Tianjin, China, has found hope after enduring years of serious medical challenges related to Type 1 diabetes.
This autoimmune disease, which affects how the body produces insulin, has dramatically changed her life since she was diagnosed at just 14 years old. For over a decade, she faced constant struggles with her health, including two liver transplants and a complete pancreas transplant.
Groundbreaking Therapy Reshapes Journey of Type 1 Diabetes Patient
Unfortunately, despite these efforts, her blood sugar levels continued to fluctuate dangerously.
Type 1 diabetes occurs when the body's immune system mistakenly attacks the pancreatic cells responsible for producing insulin, a hormone that helps control blood sugar levels.
This means that even consuming a small amount of rice would cause her blood sugar to spike to unsafe levels. Her journey included multiple transplants, but her newly transplanted pancreas had to be removed due to severe blood clots that posed life-threatening risks.
In search of a more effective treatment, she enrolled in an experimental procedure at Peking University. This innovative approach involves extracting fatty cells from her body and transforming them into insulin-producing tissues.
These tissues are then implanted into her abdomen. Remarkably, within just three months, her body started to generate insulin on its own, allowing her to stop using external insulin injections to manage her blood sugar levels.
The newly transplanted cells have remained effective for at least one year, showing no signs of losing their function or causing significant side effects. Thanks to this groundbreaking treatment, the woman can now process sugar and carbohydrates similar to someone without diabetes.
In her own words, she shared with Nature, "I can eat sugar now...I enjoy eating everything, especially hotpot."
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Pioneering Stem Cell Research Offers New Hope for Disease Treatment
The experimental treatment, published in Cell, revolves around a special type of stem cell known as induced pluripotent stem cells. These cells have the remarkable ability to revert mature cells back to a stem cell-like state.
Using a specific chemical mixture, researchers can stimulate these cells to grow into different types of tissues, including insulin-producing cells.
For the last twenty years, researchers have been trying to convert adult tissues into pluripotent stem cells, but previous results have been inconsistent, according to Science Alert. The team at Peking University believes their method provides better control over the results, leading to successful outcomes for patients.
The findings align with other clinical trials indicating that stem cell transplants may hold significant potential for treating various diseases.
The researchers at Peking University remarked, "Overall, the findings support further clinical studies in this direction and mark a step forward in achieving the potential of personalized cell therapy... to treat disease."
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