Electronic Cigarettes May Cause Cardiac Electrical Dysfunction, New Study Claims

E-cigarettes are really a comparatively fresh tobacco product that has been offered in the United States for approximately a decade. The Food and Drug Administration has not conducted a systematic study of the e-cigarettes currently on the market to establish their impact on lung health. While much needs to be discovered about the long-term health effects of these devices, the American Lung Association is deeply concerned about the emerging research regarding the damage of e-cigarettes on the lungs, as stated in their report.

A recent analysis from the Christina Lee Brown Envirome Institute at the University of Louisville discovered that exposure to e-cigarette aerosols can trigger cardiac arrhythmias in animal studies, both in the manner of premature and missed heartbeats. The conclusions of the study, published on October 25 in Nature Communications, imply that exposure to certain compounds found in e-cigarette liquids (e-liquids) promotes arrhythmias as well as cardiac electrical dysfunction.

The study's lead author Alex Carll mentioned that their study's findings show that brief exposure to e-cigarettes might alter cardiac rhythm using particular compounds in e-liquids. It will also imply that e-cigarette usage using specific flavors or solvent carriers may disturb the electrical conduction of the heart and cause arrhythmias, the assistant professor in the University of Louisiana Department of Physiology added.

E-Cigarettes' Harmful Impact on Cardiac Wellness

The cardiac effects of inhaled e-cigarette aerosols derived only from the two primary constituents in e-liquids (nicotine-free propylene glycol and vegetable glycerin) and from gourmet retail e-liquids electronic cigarettes were also studied. Scientists discovered that, when exposed to all e-cigarette aerosols, the animals' heart rates reduced during puff exposure and then increased when heart rate variability decreased, indicating fight-or-flight chronic stress. Furthermore, e-cigarette puffs containing menthol-flavored e-liquid or propylene glycol solely resulted in ventricular arrhythmias as well as other conduction anomalies in the heart as stated by a report from Medical Xpress.

This research, conducted in collaboration with Daniel Conklin as well as Aruni Bhatnagar, faculty members in the UofL Division of Environmental Medicine, contributes to a growing body of knowledge on the potential toxicity and health consequences of electronic cigarettes identified by the American Heart Association Tobacco Regulation and Addiction Center, of which UofL serves as the flagship institute.

The outcomes of such studies are significant because they give fresh information that the consumption of e-cigarettes can interfere with normal cardiac rhythms - something the masses didn't know previously. This is quite alarming due to the increasing development of e-cigarette usage, particularly among young people, as per Bhatnagar.

A study from the University of Louisiana suggests that cardiac disease can be derived from e-cigarettes’ liquids.
Alex Carll, assistant professor in the UofL Department of Physiology, front, with Matthew Nystoriak, associate professor of medicine. University of Louisville

E-Cigarettes' Popularity in Modern Times

As e-cigarette usage has increased across the country, the benefits and drawbacks of vaping have already been discussed. Because vaping somehow doesn't involve combustion, users or bystanders are exposed to very little, if any, carbon monoxide, tar, or cancer-causing nitrosamines as compared to traditional cigarettes.

E-cigarettes, on the other hand, can release aldehydes, particulates, and nicotine in quantities equivalent to traditional cigarettes. While vaping may help smokers stop smoking, the attractiveness and addictive properties of e-cigarettes may drive kids to vape despite uncertain long-term hazards or to start smoking. Before the epidemic, over 25% of high schoolers, including 10% of middle schoolers in the United States, reported smoking e-cigarettes.

Carll and Matthew Nystoriak, an assistant professor of medical sciences at the University of Louisville, recently obtained $3.6 million in scientific funding from the National Institutes of Health to investigate the effects of vape flavorings on the heart. Carll said that their team's analysis claims that particular compounds in e-cigarette liquids induce arrhythmias suggesting that greater study into the cardiac consequences of such substances in both animals and people is urgently needed, as Eurekalert reports.

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