The process of stopping one's age or at least slowing it has been the topic of many scientific research. As such, new studies showed that a mouse had successfully slowed its aging after it received younger blood.
Blood Transfusion Effect on Aging
According to the story by Newsweek, this study has many similarities to what some people might imagine coming from science fiction. This comes as scientists have been able to expand the lives of older mice through blood transfusion.
The findings of the scientists were that these older mice lived 10% longer by blood transfusion. The results happen as their bloodstreams were fused with those of younger mice.
Newsweek reports that this was a first for the team, which discovered that young blood transfusion could have significant anti-aging effects. They also found that the effects lasted for months; and should this method also be used on humans, it could have longer results.
The scientists estimate that should the same blood transfusion method be used on humans, this could extend their lives by five to seven years. Despite the successful results of the study, discovering the effects of slowing aging processes isn't that new.
Exploration of Blood Transfusion
Abrosia, a California-based startup, started selling young blood liquid components back in 2017 with the intent of them being used for transfusions. The company sold their liquid components for $8,000 a liter, but their business didn't last for long.
According to Business Insider, in 2019, the Food and Drug Administration issued a warning about their technology, which ultimately led to their closure. However, research in the field of blood transfusion still continues with more scientists yielding positive results.
The method used in blood transfusion came from the mid-1800s which involved parabiosis, including surgically fusing two animals together through surgery. With regard to anti-aging, this method was first used by Stanford University researchers in 2005.
Parabiosis in Mice
James White, a Duke University School of Medicine and Duke Aging Center professor of medicine and cell biology, described how parabiosis worked with mice. As such, he said that the method connected tissue between two mice, allowing them to share circulation.
White who led the study gave a statement to Newsweek regarding the detachment procedure. He said that to do this, the connection between the two mice need simply be separated and that the mice would easily recover.
The study was published in the Nature Aging journal, where he and his team did the experiment and looked for quantitative data regarding the method's anti-aging benefits. White said that the results surpassed their anticipations, saying the effects lasted longer than they expected.
The old mice showed reduced biological aging two months after the detachment happened. They also found its gene expression as the same with younger mice.
White specified how the results suggest that reaching a more youthful state could be possible with cellular reprogramming over time.
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