It is of great discomfort when diarrhea pathogens strike in your intestines. If left untreated, these bacteria infesting our innards will harm and slowly destroy the tissues of the intestinal linings. In effect, the pathogens continue to grow and may spread throughout the human body. Vaccination is a remedy to rid the system of these harmful pathogens.
Vaccination protects the body from harmful bacteria and viruses. The infusion of friendly pathogens allows the body to reinforce itself with protective antibodies (lgA). These secretory protective antibodies are successful in fighting off some intestinal infections.
It was not clear before how the vaccination induced protective antibodies to defend the system from infections. However, a research team led by Senior Assistant Emma Slack of The Federal Institute of Technology Zurich (ETHZ), had proven that the protective antibodies do its work by using samples of "Salmonella based diarrhea pathogens and how lgA works on them, as reported by Science Daily.
The scientists and researchers have now given the public a clear cut view of how vaccinations combat bacterial intestinal illnesses. Infused friendly pathogens, directing the body to produce protective antibodies (lgA), chain up harmful pathogens as they grow and infest the intestines. This action prevents the disease and also stops the breakout of antibiotic resistance of the bacterium.
Chaining the harmful pathogens together binds the offspring of the bacteria when it mutates. The daughter mutation is tied up in a lump and could not free itself from the chains binding it as the multiplying of bacteria continue. Bacteria in chains prevent them from attacking intestinal tissues and hinders it from interacting with other pathogens also lumped together by the protective antibodies, as reported by ETH Zurich.
The bacteria and the preventive antibodies lump are known as "agglutination". This helpful process is possible with the abundance of bacteria and antibodies and is in direct contact with each other. The lgA hang tightly to the pathogens that even their offsprings cannot get out of bondage.
Dr. Wolf Dietrich Hardt, Professor of Microbiology at ETHZ says that the clump formation does not kill the pathogens, they only chain them, otherwise, a bacterial battle will ensue which will result in a violent immune response. The chains prevent the infection of the host and interaction with other pathogens. The clumps are then disposed of via feces harmlessly.
