DNA has long been considered as an important unit of life in medical science. DNA damages can cause potential disease like Cancer and more. Thus to overcome such issues an ample number of studies have been evolved on DNA repairing for a long time. But none of these has had been able to convey a real result until now. Recently, a group of researchers achieved such a milestone in their research for new sort of DNA repairing which can make up trustworthy measures for Cancer treatment.
According to Phys, Chromosomes go through DNA repairing process to resolve wrong genetic codes, due to either incorrect DNA sequencing or for external factors. The majority, of these wrong codes, get resolved in the process unaffecting the cell growth. But some of the errors become permanent causing mutational issues like cancer. double-strand DNA breaks (DSB) are most dangerous among these. According to the scientists, DSBs can be fixed by matching and repairing the last ends of the affected chromosomes. The innovation was evolved by postdoctoral fellow Ranjith Anand with contributions by technician Annette Beach and physics Ph.D. student Kevin Li. who carried the process on yeast cells.
As per a report by Nature Journal, the matching up of the broken chromosomes with the right DNA sequences is not an easy task to do. Gathering the right template is the most crucial part in this target. This process evolves with the correct sequencing of DNA contents like the molecules guanine and cytosine or adenine and thymine. And this is only possible with the RAD51 protein, which, according to the researchers "promotes the matching up of the broken end with potential donor sequences."
The correct and proper templates of DNA sequence can only be achieved with the support of RAD51. It mediates the search for the correct DNA from a lot of chromosomes and thereby supports to connect that in the right segment.
