The research team at The Estee Lauder Companies Inc. (NYSE: EL) Research & Development (R&D) will present research focused on new findings in skin defense and anti-aging study at the 2019 Society for Investigative Dermatology Meeting (SID) in Chicago.
As a global leader with the capability to understand how environmental factors impact the skin, The Estee Lauder Companies' R&D team tops the list. Human skin is their first barrier of protection against potential environmental stressors such as pollution and UV. Also shown by the studies was how crucial cutting-edge ingredients could aid skin defense and response using their natural capabilities. The following summarizes the research of the Estee Lauder Companies' R&D team that will be presented at the 2019 SID meeting:
The Estee Lauder Companies' R&D team has found how each sirtuin isotype is essential to skin cell activity, and the activation of sirtuins with critical ingredients can impact and increase the activity of skin fibroblasts to help combat aging. Also, the research of the Estee Lauder Companies' R&D team has shown that another critical ingredient, Eucalyptus globules extract has significant antioxidant activity that can help the skin to defend against oxidative stress from pollution, UV or blue light to reduce associated oxidative damage.
Kurt Schilling, Ph.D., Senior Vice President, Basic Science Research and Advanced Technology, Research and Development, The Estee Lauder Companies said that the company's R&D team is at the forefront of understanding the impact that environmental stressors have on the barrier of the skin and the effect it has on skin aging. Schilling said that as their scientific research continues to uncover key anti-aging ingredients and better understand the biological mechanisms behind aging, they will continue to apply this knowledge to help define and advance the future of beauty for their global consumers.
There has been increasing evidence that demonstrated the importance of Sirtuins in longevity, metabolism, and control of stress. Sirtuins are evolutionary well-conserved proteins found in mammalian cells and include seven isotypes. Sirtuins function primarily as NAD-dependent deacetylases, although two of the seven have ribosyltransferase activity - the collapse of local chromatin results in the modulation of transcriptional programs involved in metabolism and inflammation.
This research reveals that by combining a flower extract which activates Sirt-1, algae extract which activates Sirt-3, and a ferment which activates Sirt-6, there is an impact and increase in the activity of 62-year-old skin fibroblasts.
