Both pharmaceutical and medical advancement are on its way as scientists are currently studying a new drug to counteract antimicrobial resistance (AMR). The study was headed by Dr. Ishwar Singh together with his team from the School of Pharmacy, one of the colleges of University of Lincoln, United Kingdom.
In 2015, USA scientist discovered Teixobactin a drug that kills pathogens which prove its antimicrobial ability. According to Science Daily, Teixobactin was isolated from microorganisms that are found in soil. The University of Lincoln then produced synthetic derivatives of Teixobactin which opened a new gate in battling AMR.
The different derivatives of Teixobactin that was synthetically synthesized by Dr. Singh and his team were biologically tested by Dr. Edward Taylor. The team was able to discover that the molecular structure of the antimicrobial agent is directly related to its antimicrobial spectrum or bactericidal efficacy.
Specifically, the disoriented and unstructured form of teixobactin promotes the effective biological activity of the drug as compared to its oriented and structured form. Thus, the team was also able to identify the way to maintain the disoriented structure of the drug maintaining also its antimicrobial efficacy.
Dr. Singh stated that they have successfully defined the molecular structure of the seven teixobactin analogs including the different amino acids and their contribution to the pharmacologic and antimicrobial efficacy of the drug. It was further revealed by Dr. Taylor that extensive research regarding the structure of the different versions of teixobactin will enable them to produce a drug with the best pharmacologic and pharmaceutical properties in a larger scale.
According to World Health Organization, antimicrobial resistance is the ability of bacteria, virus, and parasites to overcome the effects of commercially available antibiotics that possess a different spectrum of activity. Antimicrobial resistance has been a great challenge in the healthcare industry worldwide packed up with different evolving bacterial and viral infections.
Because of the public's wrong choice of medication and antibiotic drug misuse antimicrobial resistance was truly evident in every country. This newest discovery regarding the eradication and addressing AMR issues is surely a great help in the medical and pharmaceutical platform. Meanwhile, get to know the newest update on polio vaccine; click here for more information.
